Role at a glance
- Job function
-
Engineering & R&D Biotechnology & Pharmaceutical R&D
- Salary
- $68.6K – $114.3K/yr
- Location
- Pearl River, New York, United States
- Work arrangement
- On-site
- Employment
- Full-time
- Experience
- B.S. degree with 3 to 5 years of relevant industry or research experience, or M.S. in bioengineering, biochemistry, chemical engineering...
- Education
- B.S. degree with 3 to 5 years of relevant industry or research experience, or M.S. in bioengineering, biochemistry, chemical engineering...
- Visa support
- U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
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Role Summary
The Senior Associate Scientist will join Pfizer’s Early Bioprocess Development group within the Vaccines organization. The role supports development of high-quality protein subunit vaccines through cell line development, fermentation, molecular biology, and data-driven process optimization.
What You'll Do
- Optimize cell line development workflows to improve protein expression, productivity, process efficiency, and biological robustness
- Execute fermentation and characterize cell fitness, growth, recovery, protein production yield, and protein purity
- Analyze data to identify patterns and establish quantitative correlations between input parameters and protein yield and quality
- Present experimental data and strategic conclusions at cross-functional meetings
- Maintain records in Electronic Laboratory Notebooks and author technical and production reports
- Draft, review, and contribute to internal technical reports and external scientific publications
Generated from the employer's posting. Verify important details before applying.
View full postingQualifications
Experience in aseptic cell culture techniques, flow cytometry and cell sorting cytometers, flow cytometry analysis software such as FlowJo, and molecular biology techniques including DNA/RNA extraction, PCR, ddPCR, RT-PCR, ligation, cloning, transformation, gel electrophoresis, SDS-PAGE, western blot, and ELISA. Strong collaborative spirit, communication skills, organization, self-motivation, teamwork, and attention to detail.
Required
- Aseptic cell culture techniques, including cell passaging and maintenance, transfection, monitoring cell morphology and viability
- Flow cytometry and cell sorting cytometers
- Flow cytometry analysis software such as FlowJo
- DNA/RNA extraction
- PCR
- ddPCR
- RT-PCR
- Ligation
Preferred
- Experience in setting up, feeding, sampling and controlling benchtop or single-use bioreactors (batch, fed-batch)
- Hands-on knowledge and experience with NGS sequencing platforms
Original job description
Content provided by the employer
Original job description
Content provided by the employer
Why Patients Need You
Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. Process Development is at the heart of fulfilling this purpose as we translate advanced science into streamlined, robust processes that deliver medicines to patients globally.
What You Will Achieve
As a Senior Associate Scientist within the Early Bioprocess Development (EBPD) group in the Vaccines organization, you will apply cutting-edge technologies to accelerate the development of high-quality protein subunit vaccines. This role is highly technical and collaborative, requiring deep hands-on expertise in molecular biology, cell culture, and data-driven process optimization.
Your goals will be:
Optimize cell line development workflows to improve subunit protein expression, overall productivity, process efficiency and biological robustness of the production systems
Execute fermentation to characterize key performance indicators including cell fitness, growth, recovery, protein production yield, protein purity etc.
Perform data analysis to identify patterns, establishing quantitative correlations between input parameters such as DNA sequences and output values such as protein yield and quality.
Present experimental data and strategic conclusions at cross-functional meetings, contributing to team-wide knowledge sharing.
How You Will Achieve It
Collaborating with multi-disciplinary teams and working closely with the cell culture, purification, mRNA production and analytical groups.
Maintain impeccable, timely records in Electronic Laboratory Notebooks (ELNs) and author comprehensive technical/production reports.
Draft, review, and contribute to internal technical reports and external scientific publications.
Contribute to building a culture that embraces excellence, urgency, partnerships with key stakeholders, continuous learning and improvement, increasing technical skill base and other cross-functional expertise.
Ensure all tasks and responsibilities are carried out according to scientific, ethical and regulatory standards.
Qualifications
Must-Have
B.S. degree with 3 to 5 years of relevant industry or research experience, or M.S. in bioengineering, biochemistry, chemical engineering or related fields with 0 to 3 years of experience
Experience in aseptic cell culture techniques, including cell passaging and maintenance, transfection, monitoring cell morphology and viability.
Experience in using flow cytometry, and cell sorting cytometers as well as flow cytometry analysis software such as FlowJo.
Knowledge and hands-on experience in molecular biology techniques including DNA/RNA extraction, PCR, ddPCR, RT-PCR, ligation, cloning, transformation, gel electrophoresis, SDS-PAGE, western blot, ELISA.
Well organized, self-motivated, team-oriented with high attention to detail.
Strong collaborative spirit and communication skills.
Nice-to-Have
Experience in setting up, feeding, sampling and controlling benchtop or single-use bioreactors (batch, fed-batch)
Hands-on knowledge and experience with NGS sequencing platforms.
OTHER JOB DETAILS
Work Location Assignment: On site
Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email [email protected]. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers.
Research and DevelopmentAbout the company
Pfizer
Large Enterprise
Pfizer is a global biopharmaceutical company dedicated to the discovery, development, and manufacturing of innovative healthcare solutions. With a strong focus on improving lives through medications and vaccines, Pfizer has played a significant role in addressing various health challenges, including infectious diseases, chronic illnesses, and rare conditions. The company emphasizes research-driven approaches and collaborative efforts in its mission to enhance global health and empower patients through cutting-edge science and technology. Through its commitment to high standards of safety and efficacy, Pfizer continues to shape the future of medicine.