Role at a glance
- Salary
- Not yet verified Check the description for pay details; an amount or pay period has not been verified.
- Location
- South San Francisco, United States
- Work arrangement
- On-site
- Employment
- Full-time
- Experience
- A minimum of 5 years post-PhD experience with a record of high-impact publications (preprints considered), patents, and/or a proven track record advancing therapeutic candidates from pipeline entry to early clinical development
- Education
- PhD and postdoctoral training in Immunology, Cell Biology or related field
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Role Summary
Leads a research group focused on designing next-generation cell therapies for autoimmune diseases. The role advances research and therapeutic candidates from preclinical studies toward early clinical development, working across scientific and development functions.
What You'll Do
- Lead and manage a research team.
- Generate original research to advance understanding of autoimmune disease.
- Identify targets and therapeutic hypotheses with cross-functional teams.
- Contribute to initiating and advancing pipeline projects, including moving therapeutics from preclinical studies into early clinical...
- May participate in cross-functional evaluations of external business development opportunities for the cell therapy pipeline.
Generated from the employer's posting. Verify important details before applying.
View full postingQualifications
PhD and postdoctoral training in Immunology, Cell Biology, or a related field; a minimum of 5 years of post-PhD experience; a record of high-impact publications (preprints considered), patents, and/or advancing therapeutic candidates from pipeline entry to early clinical development; expertise in cellular immunology and autoimmune disease pathways and immune cell types; leadership and multidisciplinary collaboration skills; excellent written and verbal communication; and critical thinking, rigorous experimental design, creative problem-solving, and data-driven scientific decision-making.
Preferred
- Expertise in both B cell and T cell biology
- Experience engineering, modifying, and functionally evaluating human immune cells
- Experience working with mouse models, including humanized models
Original job description
Content provided by the employer
Original job description
Content provided by the employer
THE OPPORTUNITY
The Department of Immunology Discovery at Genentech is excited to announce an opportunity for a Principal Scientist, Lab Head, to lead a research group focused on designing next-generation cell therapies to treat autoimmune diseases.
The successful candidate will lead a highly productive research team, integrating efforts across cross-functional teams to identify new targets and therapeutic hypotheses, and to advance transformative therapeutics from preclinical studies into early clinical development. The ideal candidate will have a deep understanding of cellular immunology principles and pathways relevant to the biology of autoimmune disease, including but not limited to inflammatory bowel disease, multiple sclerosis, lupus and chronic obstructive pulmonary disease. Excellent communication skills are essential to facilitate fruitful collaborations with colleagues across a diverse array of departments, including computational biology, proteomics and tissue genomics, drug development, early clinical development, and translational medicine.
Key responsibilities include leading and managing a highly-productive research team, generating high-quality, original research that advances our understanding of autoimmune disease and contributing directly to the initiation and advancement of novel pipeline projects. The successful candidate may also play a critical role within cross-functional teams evaluating external business development opportunities to accelerate our cell therapy pipeline.
WHO YOU ARE
The ideal candidate will have:
PhD and postdoctoral training in Immunology, Cell Biology or related field
A minimum of 5 years post-PhD experience with a record of high-impact publications (preprints considered), patents, and/or a proven track record advancing therapeutic candidates from pipeline entry to early clinical development
Demonstrated expertise in cellular immunology and a deep understanding of pathways and immune cell types that contribute to autoimmune disease
Outstanding leadership and a collaborative spirit, with a proven track record of working with multidisciplinary teams
Excellent written and verbal communication skills, with the ability to communicate complex scientific concepts to multidisciplinary audiences
Exceptional critical thinking skills, a commitment to rigorous experimental design and creative problem-solving, and a demonstrated ability to use data-driven insights to guide scientific decisions
Preferred qualifications:
Expertise in both B cell and T cell biology
Experience engineering, modifying, and functionally evaluating human immune cells
Experience working with mouse models, including humanized models
Relocation benefits are available for this job posting.
The expected salary range for this position based on the primary location of California is $143,200 to $265,900. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
About the company
Genentech
Large Enterprise
Genentech, a member of the Roche Group, is a biotechnology company focused on discovering, developing, manufacturing, and commercializing innovative medicines for patients with serious medical conditions. Founded in 1976, Genentech has played a pioneering role in the biotech industry, particularly in the development of targeted therapies for cancer and other diseases. The company is committed to advancing science and addressing unmet medical needs through cutting-edge research and collaboration, making it a leader in the field of biotechnology. With a strong emphasis on sustainability and corporate responsibility, Genentech is dedicated to improving patient outcomes and enhancing healthcare globally.