Role at a glance
- Salary
- Not yet verified Check the description for pay details; an amount or pay period has not been verified.
- Location
- South San Francisco, United States
- Work arrangement
- On-site
- Employment
- Full-time
- Education
- PhD
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Role Summary
The Scientist 3 in the Hanna Lab investigates biological mechanisms and potential therapeutic targets for inflammatory diseases, with a focus on T-cell biology and immunoregulatory pathways for restoring immune and tissue homeostasis. The role advances discovery projects toward early clinical development through experimental research and collaboration across related functions.
What You'll Do
- Lead research projects on cellular and molecular mechanisms of T-cell biology and immunoregulatory pathways.
- Generate proof-of-concept data to advance pipeline programs from discovery toward early clinical development.
- Design and execute experiments using primary cell isolation, multi-dimensional flow cytometry, and complex disease models.
- Explore biological pathways to identify and validate therapeutic targets for inflammatory diseases.
- Collaborate with colleagues in human genetics, biomarker discovery, and early clinical development, and present findings at scientific...
Generated from the employer's posting. Verify important details before applying.
View full postingQualifications
PhD in Immunology, Molecular Biology, Biochemistry, or a related field, with a strong research track record demonstrated by high-quality publications. Hands-on expertise in cellular and molecular immunology techniques, including primary cell isolation, multi-dimensional flow cytometry, in vitro immunological assays, and in vivo animal models; experience independently designing, executing, and interpreting complex scientific experiments. Strong communication and collaborative skills.
Required
- Hands-on expertise in cellular and molecular immunology techniques, including primary cell isolation, multi-dimensional flow cytometry,...
- Experience independently designing, executing, and interpreting complex scientific experiments
- Strong communication and collaborative skills
Preferred
- Experience in T cell biology and/or mucosal immunology
- Experience with analysis of data from genomic sequencing, scRNA-seq, TCR-seq, CITE-seq or spatial transcriptomics
- Experience in culturing 2D and 3D murine or human organoids or other complex in vitro systems
Original job description
Content provided by the employer
Original job description
Content provided by the employer
The Hanna Lab in the Department of Immunology at Genentech is seeking a highly talented, driven and motivated Scientist 3 to investigate novel biological mechanisms and potential therapeutic targets to treat inflammatory diseases. The successful candidate will lead projects that advance our understanding of the cellular and molecular mechanisms of T cell biology, with a main emphasis on harnessing immunoregulatory mechanisms for reestablishing immune and tissue homeostasis under inflammatory conditions.
The Opportunity
Lead innovative research projects focused on understanding cellular and molecular mechanisms of T cell biology and immunoregulatory pathways.
Drive pipeline programs from discovery toward early clinical development by generating robust proof-of-concept data.
Design and execute experiments using state-of-the-art technologies, including primary cell isolation, multi-dimensional flow cytometry, and complex disease models.
Explore novel biological pathways to identify and validate new therapeutic targets for inflammatory diseases.
Collaborate cross-functionally with team members across human genetics, biomarker discovery, and early clinical development.
Present research findings regularly at intra- and inter-departmental meetings, fostering an open and inquisitive scientific culture.
Who You Are
You hold a PhD in Immunology, Molecular Biology, Biochemistry, or a related field with a strong track record of research achievement in the form of high-quality publications
You possess hands-on expertise in cellular and molecular immunology techniques, including primary cell isolation, multi-dimensional flow cytometry, in vitro immunological assays, and in vivo animal models.
You have experience independently designing, executing, and interpreting complex scientific experiments.
You bring strong communication and collaborative skills, thriving in an open, team-oriented laboratory environment.
You are curious, open-minded, and passionate about advancing science to uncover novel biological mechanisms.
Preferred
Experience in T cell biology and/or mucosal immunology.
Experience with analysis of data from genomic sequencing, scRNA-seq, TCR-seq, CITE-seq or spatial transcriptomics is preferred.
Experience in culturing 2D and 3D murine or human organoids or other complex in vitro systems is a plus.
Together, we’ll advance along the whole patient journey with the aspiration to prevent, stop and cure diseases.
Relocation can be offered for this position
The expected salary range for this position based on the primary location of California is $103,400 - $192,000. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
About the company
Genentech
Large Enterprise
Genentech, a member of the Roche Group, is a biotechnology company focused on discovering, developing, manufacturing, and commercializing innovative medicines for patients with serious medical conditions. Founded in 1976, Genentech has played a pioneering role in the biotech industry, particularly in the development of targeted therapies for cancer and other diseases. The company is committed to advancing science and addressing unmet medical needs through cutting-edge research and collaboration, making it a leader in the field of biotechnology. With a strong emphasis on sustainability and corporate responsibility, Genentech is dedicated to improving patient outcomes and enhancing healthcare globally.