Genentech

Genentech

Posted via Workday

Postdoctoral Fellow - Multimodal Technologies & Complex Human Models, Regev and Chen Labs

Posted Oct 27, 2026

Role at a glance

Job function
Engineering & R&D Biotechnology & Pharmaceutical R&D
Salary
$100K – $106.5K/yr
Location
South San Francisco, United States
Employment
Full-time
Experience
Must have advanced at least one key research project as evidenced by a first-author paper published or accepted in a leading peer-reviewed journal, or on Biorxiv
Education
Ph.D. with a proven track record of excellence in single-cell genomics, spatial-omics, imaging, bioengineering, biophysics, quantitative...

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Role Summary

AI-generated

Postdoctoral Fellow position in the Regev and Chen Labs to develop single cell and spatial omics platforms for screening complex human in vitro models to accelerate target discovery. The role focuses on new experimental and computational methods for characterizing cellular responses to perturbations.

What You'll Do

  • Develop scalable measurement tools to acquire molecular, imaging and functional readouts from perturbation studies in in vitro complex...
  • Design and execute multimodal functional genomics screens to investigate mechanisms underlying disease cellular and tissue states
  • Collaborate with computational biologists and AI scientists to integrate and interpret multimodal data and explore predictive modeling...
  • Collaborate across labs and departments, present work to project teams, and contribute to high-impact scientific publications

Generated from the employer's posting. Verify important details before applying.

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Qualifications

Ph.D. with a track record in single-cell or spatial omics and assay development, plus fluent Python programming and hands-on experimental skills.

Required

  • Ph.D. with a proven track record of excellence in single-cell genomics, spatial-omics, imaging, bioengineering, biophysics, quantitative...
  • Must have advanced at least one key research project as evidenced by a first-author paper published or accepted in a leading...
  • Strong hands-on experience in molecular biology, functional genomics, single-cell genomics, and/or spatial-omics
  • Experience with complex mammalian cell culture
  • Computational experience spanning single cell genomic or spatial data analysis, with a track record of programming fluently in Python or...
  • Independent scientist with outstanding communication skills and a strong passion and commitment to science, who works well within a team

Preferred

  • Experience in iPSC-cell models, organoids or 3D cultures

Original job description

Content provided by the employer

Why Genentech

We advance science so that we all have more time with the people we love.


A Postdoctoral Fellow position is available for a highly motivated and independent scientist to develop novel single cell and spatial omics platforms to screen next generation complex human in vitro models in order to accelerate target discovery. The candidate will develop new experimental and computational methods to characterize cellular responses to perturbations and generate high-dimensional datasets that enable a deeper understanding of disease biology. 

This is a hands-on position for a scientist passionate about assay development as well as engaging in state-of-the-art computational tools, including and especially AI. You will join a collaborative, cross-disciplinary environment and will have the opportunity to contribute to high-impact scientific publications.


The Opportunity:

  • Novel Assay Development: Develop scalable measurement tools to acquire molecular, imaging and functional readouts from perturbation studies in in vitro complex models
  • Large-Scale Screening: Design and execute multimodal functional genomics screens to investigate mechanisms underlying disease cellular and tissue states.
  • Computational Methods: Collaborate with computational biologists and AI scientists to develop approaches for integrating and interpreting multimodal data, and explore predictive modeling strategies to power Lab-in-the-Loop.
  • Collaborative Research: Collaborate productively with experimental and computational scientists across labs and departments, present your work to project teams, and contribute to high-impact scientific publications.
  • Professional Development: Join Genentech’s postdoctoral training program, which provides an outstanding environment and the opportunity to pursue fundamental scientific questions while building methods that drive breakthrough discoveries in drug development.

Who You Are:

  • Ph.D. with a proven track record of excellence in single-cell genomics, spatial-omics, imaging, bioengineering, biophysics, quantitative biology, or a related field, with hands-on experimental expertise.
  • Must have advanced at least one key research project as evidenced by a first-author paper published or accepted in a leading peer-reviewed journal, or on Biorxiv.
  • Strong hands-on experience in molecular biology, functional genomics, single-cell genomics, and/or spatial-omics 
  • Experience with complex mammalian cell culture, with experience in iPSC-cell models, organoids or 3D cultures a plus
  • Computational experience spanning single cell genomic or spatial data analysis, with a track record of programming fluently in Python or a comparable language.
  • Independent scientist with outstanding communication skills, a strong passion and commitment to science, who works well within a team.

Postdoc Program

Elevate your research career to new heights with Genentech’s Postdoctoral Program! Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology and bioengineering. With competitive salaries and fully funded research expenses, you can dedicate yourself to groundbreaking research that aligns with Genentech strategic ambitions.

The postdoc program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader. 


The Genentech Postdoc Program provides access to world-class seminars, professional development workshops, and networking opportunities. Apply now to Genentech Postdoctoral Program and unlock your full potential!


The expected salary range for this position based on the primary location of California is $100,000 to $106,500 . Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.  This position also qualifies for the benefits detailed at the link provided below.


Benefits

Relocation benefits are available for this job posting.


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Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

Genentech

About the company

Genentech

Large Enterprise

Genentech, a member of the Roche Group, is a biotechnology company focused on discovering, developing, manufacturing, and commercializing innovative medicines for patients with serious medical conditions. Founded in 1976, Genentech has played a pioneering role in the biotech industry, particularly in the development of targeted therapies for cancer and other diseases. The company is committed to advancing science and addressing unmet medical needs through cutting-edge research and collaboration, making it a leader in the field of biotechnology. With a strong emphasis on sustainability and corporate responsibility, Genentech is dedicated to improving patient outcomes and enhancing healthcare globally.